About Me

Hi! I'm a PhD student working with the von Meyenn lab at ETH Zürich and the Robinson Lab at the University of Zürich. Prior to that, I got my Master's degree in Computational Biology and Bioinformatics at ETH Zürich in 2021, and my Bachelor's degree in Biotechnology at HIT in 2018.

Current Research Focus

My research interests lie in two aspects:

• Method research that contributes to the standardization of single-cell epigenomic (ATAC-seq, CUT&Tag and DNA methylation) data analysis.
• The application of machine learning and systems biology approaches in biomedical problems.

Publications

• Luo, S., Germain, P. L., Robinson, M. D., & von Meyenn, F. (2024). Benchmarking computational methods for single-cell chromatin data analysis. Genome Biology, 25, 225.
  DOI: https://doi.org/10.1186/s13059-024-03356-x.
  [GitHub repo] [Software]

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• Robinson, M. D., Cai, P., Emons, M., Gerber, R., Germain, P. L., Gunz, S., Luo, S., ..., Mallona, I. (2024). "Ten simple rules for computational biologists collaborating with wet lab researchers." PLOS Computational Biology 20, no. 6: e1012174.
  DOI: https://doi.org/10.1371/journal.pcbi.1012174.
  

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• Bonder, M. J., Clark, S., Krueger, F., Luo, S., Agostinho de Sousa, J., Hashtroud, A. M., ... & von Meyenn, F. (2023). Single cell DNA methylation ageing in mouse blood. bioRxiv, 2023-01.
  DOI: https://doi.org/10.1101/2023.01.30.526343.
  

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• Luo, S., Pelissier, A., Stratigopoulou, M., Guikema, J. E., & Rodríguez Martínez, M. (2023). Exploring the impact of clonal definition on B-cell diversity: implications for the analysis of immune repertoires. Frontiers in Immunology, 14, 1123968.
  DOI: https://doi.org/10.3389/fimmu.2023.1123968.
  [GitHub repo] [Software]

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Other Research Experience

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• Analyzing cell-free DNA fragmentation patterns using sequencing data of clinical cancer samples
• Semester project, Krauthammer Lab, University Hospital of Zürich
  Dec. 2020 - Mar.2021
• 
  Supervisor: Michael Krauthammer

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• Developing mixture model-based methods to infer the ploidy of cancer genomes and the purity of tumor samples
• Semester project, Computational Epigenetics of Cancer Lab, D-INFK, ETHZ
  Dec. 2019 - Sep. 2020
• 
  Supervisor: Valentina Boeva

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• Detection of Falsified Interviews in Surveys of Households in Crisis Regions
• Volunteer Project with IMPACT Initiatives (NGO in Geneva, Switzerland)
  Sep. 2020-Nov. 2020


• Developing machine learning model to identify falsified data in humanitarian surveys.
[report] [code]

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